COPD: Understanding chronic obstructive pulmonary disease and its home healthcare support
Chronic obstructive pulmonary disease (COPD) is a debilitating and underdiagnosed chronic respiratory disease. It represents a major public health problem, as it is the fourth leading cause of death worldwide1. Characterized by permanent and progressive airway obstruction, COPD progresses slowly, initially manifesting as a chronic cough and shortness of breath that is disproportionate to the level of exertion. It cannot be cured, but its progression can be slowed with appropriate treatment. Air Liquide Healthcare, a leader in home healthcare for respiratory conditions, supports people living with this disease in their daily lives with the goal of improving their quality of life. This page offers a comprehensive guide to understanding COPD, its symptoms, its diagnosis (via spirometry), available treatments (smoking cessation, bronchodilators, oxygen therapy, NIV), and personalized daily care support.
- COPD (Chronic Obstructive Pulmonary Disease) is a chronic respiratory pathology characterized by progressive and permanent airway obstruction.
- COPD is the fourth leading cause of death worldwide, causing approximately 3.5 million deaths per year1.
- Smoking is the primary cause of COPD in more than 80% of cases4; occupational exposure and air pollution are aggravating factors.
- Diagnosis is based on spirometry, which measures lung function. The disease progresses through four stages of severity according to the GOLD classification7.
COPD cannot be cured, but its progression can be slowed: smoking cessation, bronchodilators, long-term oxygen therapy, noninvasive ventilation, and pulmonary rehabilitation are the cornerstones of treatment.
What is COPD?
Definition of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease, or COPD, is a particularly debilitating chronic respiratory disease characterized by permanent, slow, and progressive obstruction of the airways and lungs. Specifically, the walls of the bronchi and bronchioles thicken, and the cells produce excessive amounts of mucus, leading to a narrowing and obstruction of the airways. In addition, the pulmonary alveoli become distorted and gradually lose their elasticity. Unlike asthma, where bronchial obstruction can be completely reversed after inhaling a bronchodilator, the reduction in expiratory flow in COPD is not fully reversible. This insidious condition progresses slowly and worsens over time.
COPD by the numbers: prevalence and global impact
COPD represents a major public health problem worldwide. It is currently the fourth leading cause of death globally, causing approximately 3.5 million deaths per year1, which accounts for nearly 5% of global mortality in 2021. In a European country like France, this condition affects approximately 3.5 million people and is responsible for about 18,000 deaths each year2. Prevalence increases with age, and the disease now affects an increasing number of women, who account for 40 to 45% of patients due to the rise in smoking among women3. Unfortunately, this disease remains largely underdiagnosed, as it is estimated that about two-thirds of patients are completely unaware that they have it2.
-
4th cause of death globally
-
3.5 million deaths per year
-
⅔ patients undiagnosed
COPD, chronic bronchitis, and emphysema: what are the differences?
COPD generally encompasses two conditions:
- Chronic bronchitis is defined by a daily cough and phlegm production persisting for at least three months a year over two consecutive years.
- Emphysema, on the other hand, involves the irreversible destruction of the pulmonary alveoli, which impairs gas exchange.
Symptoms of COPD
The progression of COPD is marked by debilitating symptoms that affect respiratory function.
Early signs: cough, phlegm, shortness of breath
The disease progresses silently for many years without triggering any obvious symptoms. In smokers over the age of 40, the very first signs often take the form of a chronic cough, accompanied by phlegm or sputum, which occurs particularly in the morning upon waking. This so-called “smoker’s cough” is very often mistakenly dismissed as trivial by patients. Shortness of breath, medically known as dyspnea, then sets in very gradually. It initially appears during intense physical exertion or when walking briskly, then progressively becomes a problem for the patient even during increasingly minor, everyday activities.
Progression of symptoms across stages
Over time, the narrowing of the bronchi worsens and shortness of breath becomes significantly more severe, eventually occurring even at rest. Patients then experience episodes of exacerbations, characterized by a sudden worsening of cough, phlegm, and dyspnea, often triggered by simple infections. At a very advanced stage, this damage leads to chronic respiratory failure with a persistent lack of oxygen in the blood, requiring respiratory support.
Diagnosis and progression of COPD
The earlier the diagnosis, the better the chances of slowing the disease’s progression by accurately determining its stage.
Diagnosis via spirometry: FEV1 and FVC
A definitive diagnosis of COPD must be based on pulmonary function testing, specifically spirometry. This quick medical test very accurately measures a patient’s lung capacity and bronchial airflow. In particular, it assesses forced vital capacity (FVC) and forced expiratory volume in one second (FEV₁). Spirometry reveals an obstructive ventilatory disorder that persists, at least partially, despite the inhalation of a bronchodilator medication. This confirms the permanent and irreversible narrowing of the airways.
The 4 Stages of COPD according to GOLD
Based on the measured FEV1 value—and thus the severity of bronchial obstruction—the leading international organization GOLD (Global Initiative for Chronic Obstructive Lung Disease) has defined the progression of the disease according to four stages of increasing severity. Stage 1 describes mild obstruction, where FEV1 is greater than or equal to 80% of the normal peak expiratory volume. Stage 4 indicates very severe obstruction with an FEV1 of less than 30%7.
COPD treatments
The management of COPD aims to reduce daily symptoms and prevent sudden exacerbations to improve patients’ quality of life. While treatments cannot cure COPD, they can slow the decline in lung function.
Living with COPD on a daily basis
Respiratory rehabilitation and adapted physical activity
Respiratory rehabilitation is a major component of disease management, particularly when shortness of breath limits the patient’s ability to perform daily activities. It is a multidisciplinary program tailored to the patient’s needs that combines intense exercise retraining, physical therapy to clear the airways, psychological support, and therapeutic education. By preventing a sedentary lifestyle—which leads to loss of muscle mass and strength, reduced exercise tolerance, and impaired coordination—this approach aims to reduce shortness of breath. Engaging in regular physical activity will help restore the patient’s independence in daily life and a better quality of life by reducing the risk of hospitalization9.
Recommended vaccinations (flu, pneumococcal, COVID-19)
Patients with COPD are more vulnerable to respiratory infections, which are major causes of exacerbations. Exacerbations are defined as increased dyspnea—when shortness of breath becomes severe following minimal exertion—accompanied by an increase in coughing and copious sputum production. It is strongly recommended that people living with COPD get vaccinated against the flu every year and protect themselves against pneumococcal disease, the COVID-19 virus, and RSV.
Adapting your environment and lifestyle
Exposure to tobacco smoke and indoor pollution should be minimized as much as possible. Special attention should also be paid to ensuring a balanced diet to prevent malnutrition or, conversely, excess weight.
How Air Liquide Healthcare supports people living with COPD
Mechanical ventilation and home oxygen therapy are essential components of our home healthcare services and are experiencing rapid growth, driven by an aging population and the rising prevalence of chronic diseases. Our care distinguishes itself from a traditional approach centered on medical devices by adapting to each person’s medical condition, motivations, and specific needs. For patients, this means improving their health outcomes and receiving the necessary support when they need it. Home care is complex and critical to ensuring treatment adherence and improving patients’ quality of life. Air Liquide Healthcare, drawing on its entities dedicated to home healthcare, offers care protocols tailored to patients’ needs.
Recognized expertise in home respiratory care
Air Liquide Healthcare combines the expertise of its teams with the power of digital solutions to personalize care. Specifically, the analysis of remote monitoring data, combined with human intervention, enables us to detect early signs of treatment discontinuation or clinical deterioration, side effects, or difficulties related to the use of medical devices. All of this information is shared with the patient’s physician.
Moving away from an approach that has historically focused on medical equipment, Air Liquide Healthcare is committed to offering support plans centered on the person living with a chronic condition.
- Effect of telemonitoring on the rate of dropout
Studies have shown that close monitoring during the first months of treatment and tailoring therapy to each patient significantly contribute to improving long-term adherence (a 21 percentage point reduction in the NIV discontinuation rate at 1 year: 13% in the group with remote monitoring vs. 34% without remote monitoring, p<0.001)10.
- COPD practices across Europe
The European Panorama NIV study initiated by Air Liquide Healthcare11. Conducted among 38 clinicians in 11 countries, this survey confirmed the need to harmonize practices across countries by defining new care models for COPD patients. 30% of the physicians surveyed emphasized the need for better home-based care, and 27% called for more remote monitoring. The study also demonstrated physicians’ strong desire to delegate certain tasks—such as mask adjustments or monitoring adherence—to home healthcare providers to improve efficiency. These results enable us to engage in a constructive dialogue with payers by comparing data from multiple healthcare systems, while highlighting the need to delegate certain tasks that currently remain the responsibility of hospitals12.
- Role of home health care providers
Professors Claudia Crimi and Annalisa Carlucci published an article in the American Journal of Respiratory and Critical Care Medicine highlighting the essential role of home health care providers in the successful initiation of noninvasive ventilation (NIV) treatment at home for patients with COPD. Beyond the clinical outcomes observed, the article emphasizes the importance of patient education and support in improving health outcomes13.
Our services: oxygen therapy, ventilation, personalized care
In accordance with the issued prescription, these home-based treatments include the provision of medical devices (oxygen concentrators, ventilators, respirators), training in their use, and support for patients and their families to ensure proper adherence to therapy and manage its impact on daily life. This enables patients to take an active role in their treatment throughout their lives. Once a diagnosis and treatment plan have been established by a physician, long-term treatment requires patient support, provided by qualified nurses or technicians either in person or remotely through the increased use of digital solutions. Personalized care plans provide the support each patient needs, when they need it. Through multidisciplinary teams of experts (pharmacists, nurses, nutritionists, and technicians), Air Liquide Healthcare aims to enhance patients’ independence and improve their quality of life by ensuring treatment adherence to prevent the risk of relapse or rehospitalization.
Coordinated care with the prescribing pulmonologist
Our care model is based on very close collaboration with healthcare professionals. Information is continuously shared with them through regular meetings and access to a digital platform that consolidates remote monitoring alerts and all our visit reports or communications with patients, enabling us to work in perfect coordination. This seamless communication and close patient monitoring are designed to reduce their daily workload. Non-essential visits to the hospital or doctor’s office are avoided, allowing medical teams to focus on their most critical clinical tasks.
Key takeaways on COPD
- An underestimated disease: widely underdiagnosed but the fourth leading cause of death worldwide.
- Prevention: Smoking is responsible for 80% of cases.
- Diagnosis: Spirometry is the essential gold-standard test.
- Air Liquide Healthcare Support: Home healthcare services tailored to patients’ needs, aimed at improving their health outcomes and quality of life at the lowest possible cost to the healthcare system.
Frequently asked questions about COPD
What are the early signs of COPD?
The early signs of COPD are a persistent cough, morning sputum, and shortness of breath during physical activity. These symptoms are often dismissed as minor, particularly among smokers, which delays diagnosis. It is estimated that two-thirds of COPD cases go undiagnosed.
Can COPD be cured?
COPD cannot be cured. However, its progression can be significantly slowed by quitting smoking, appropriate medication, and pulmonary rehabilitation. Early treatment improves quality of life and life expectancy.
What are the four stages of COPD?
The GOLD classification distinguishes four stages: mild (stage 1), moderate (stage 2), severe (stage 3), and very severe (stage 4). These stages are defined by the FEV1 measurement during spirometry. The more advanced the stage, the more severe the airway obstruction.
What is a COPD exacerbation?
An exacerbation is a sudden and prolonged worsening of respiratory symptoms: increased shortness of breath, coughing, and sputum production. It can be triggered by an infection, pollution, or another respiratory condition. Each exacerbation can cause lasting damage to lung function.
What is the life expectancy for someone with COPD?
Life expectancy for a person with COPD depends on the stage of the disease at the time of diagnosis, whether or not the person has quit smoking, and the quality of care received. COPD that is diagnosed early and well managed can be stabilized for many years. Conversely, severe, untreated COPD progresses to chronic respiratory failure.
What is daily life like for someone with COPD?
Living with COPD requires making certain adjustments: quitting smoking, engaging in appropriate physical activity through pulmonary rehabilitation, getting annual vaccinations, and, for some patients, receiving home health care services. Air Liquide Healthcare, through its divisions dedicated to home health care, supports patients in their treatment.
2 French National Authority for Health (HAS). COPD – Common Causes: Smoking and Occupational Exposure. 2013/2015.
Santé publique France / CépiDC (Inserm). Epidemiological surveillance of COPD. 2016 (2014 data: > 18,000 deaths with COPD as the primary or contributing cause).
3 FEMMES ET BPCO : UN ENJEU DE SANTE PUBLIQUE
4 Inserm. Chronic Obstructive Pulmonary Disease (COPD). Thematic Report. 2023.
5 Améli: Comprendre la BPCO
6 ANSES. Collective Expert Review: COPD and Occupational Exposure. 2025.
See also: Santé Respiratoire France. Occupational COPD.
7 Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global Strategy for the Diagnosis, Management, and Prevention of COPD. 2024 Report.
8 Haute Autorité de Santé (HAS). Care Pathway Guide – Chronic Obstructive Pulmonary Disease (COPD). January 2020.
See also: Journal of Respiratory Diseases. Indications for Long-Term Oxygen Therapy in Patients with COPD or Chronic Obstructive Pulmonary Disease (COPD). 2024.
9 French National Authority for Health (HAS). How to Implement Respiratory Rehabilitation for Patients with COPD? July 2014.
10 Le Mao R, Gut Gobert C, Texereau JB, Kremer F, Goret M, Chekroun Martinot A, Rosé M, Trzepizur W, Gagnadoux F. “Effect of telemonitoring on the rate of dropout during home non-invasive ventilation: a retrospective study using a home care provider database.” BMJ Open. Oct 4, 2024;14(10):e088496.
11 Crimi and al. "Organization and delivery of home-based care for chronic obstructive pulmonary disease patients receiving long-term home non-invasive ventilation: a systematic review". European Journal of Internal Medicine,, 106880 April 13, 2026
12 Crimi C, Carlucci A, et al. “Variations in long-term home noninvasive ventilation practices for COPD across Europe: a clinician survey.” ERJ Open Research. 2026; Early View. DOI: 10.1183/23120541.01159-2025
13 Crimi C, Carlucci A. “Timing for Initiating Home Noninvasive Ventilation in Italy: Beyond Clinical Parameters.” Am J Respir Crit Care Med. March 1, 2025;211(3):520–521. DOI: 10.1164/rccm.202411-2119LE